Cell cycle by emphasizing DNA replication Research Paper

Cell cycle by emphasizing DNA replication - Research Paper Example Increase in the number of cells with 2C-DNA content attests that over expression of wild type CDC6 impacts on the cell cycle kinetics. However, this over expression has no effect on cell proliferation. After S phase is complete, CDC6-d2 on the other hand blocks cell cycle progression and inhibits proliferation as cells with 2C DNA pile up; CDC6-d2 does not inhibit DNA replication but it does passage via mitosis. When SCF CDC4 is inactive, dephosphorylation of B subunit can be driven by over expression of the wild type CDC6 in nocodazole arrested cells. This however is not the case as with when the SCF CDC4 is active as over expression of the cells does not lead to dephosphorylation of the B subunit because over expression of CDC6-d2 blocks cells in G2/M by inactivating CDC28-Clb kinase and in a CDC4+ background produces phenotype very much like that produced by the over expression of wild type CDC6 in a CDC4 mutant background. Unlike CDC6-d2 which is stable in nocodazole arrested cells, the wild type protein is not and quickly disappears into the cells thus showing CDC6-d2 as being resistant to mode 3 proteolysis. It is noted however that CDC6-d2 is not affected for mode 1 proteolysis or mode 2 proteolysis but is affected as a substrate for mode 3 proteolysis; a single point mutation yielding transformation from C to T at bp 1103 causing substitution of threonine at amino acid 368 with methionine was pointed out after DNA analysis of the CDC6-d2. There are three glycine and six proline residues in a 50 amino acid residue surrounding this region, triggering belief that this region could be unstructured (Perkins, Lusy & John, 4837). Two other regions were equally examined to check whether their muattions also had some effects on the stability of CDC6. Two CDC6 alleles were constructed using site directed mutagenesis where serine 372 was transformed to alanine (S372A) and in the other, serine 354 was changed alanine

Hip Hop Essay Example | Topics and Well Written Essays - 500 words

Hip Hop - Essay Example These men were the rebels of the day. But as hip hop has become more popular, its stars have become brands and multimillionaires too. They do not commit crimes because it would reduce their brand value. Instead, like Michael Corleone, they try to become legitimate businessmen. In the process, they sell their music as entertainment. They become the fat cats and authority figures that they once railed against. In early times they would talk about how hard their lives were and how impoverishing the ghetto was—but now they told such stories from their Manhattan penthouses. This tension causes a real problem for hip hop. The answer to the above question must be â€Å"no.† With commercialization, hip hop has lost much of its authenticity. It is no longer a product of the street, but is instead a product of the businesses and record people who sell it at Walmart. Record labels can try to fabricate and market street cred, but that does not make it authentic (Watkins, 2). Authen tic hip hop still exists in clubs and among the undiscovered, but it has lost something over the years. It is no longer as real as it once was. What does the transformation of the â€Å"hood† from an inner city location to a consciousness allow artists like Jay-Z to do? Through his music, Jay-Z is capable of transforming a physical location or state of poverty into something much more inspiring.

Importance of Strategic thinking and formulation in the organisational Essay

Importance of Strategic thinking and formulation in the organisational change - Essay Example There are many stages involved in the process of the strategic management. These steps are divided in to three broad categories: 1) Strategy formulation 2) Strategy implementation 3) Strategy evaluation The first step namely the strategy formulation involves the development of the business mission, evaluation of the opportunities and threats faced by the business organisation in the business, by using tools such as SWOT analysis, examining the strengths and weaknesses of the business, determining the long term objectives of the business and designing the new strategies to eke in the process of achieving the new targets. It also include the processes to determine the investment direction, the business markets to be addressed, extension of the operations of the business, limitations faced by the business in order to undertake the business activities.... d the marketing efforts, planning the financial issues, alignment of the information system with the information needs of the employees and last but not least provisions of appraisals and rewards to the employees. The strategy implementation stage requires several actions to be taken by the management in order to get the most of it. The successful implementation of a strategy is directly related to the ability of a manger to motivate employees in the strategic direction and to develop an organisational culture to adopt the change and take it into the daily business practise. It also demands some crucial steps by the managers on personal level. The manger should depict different qualities such as discipline, high level of commitment and motivation, leadership and enthusiasm of making things possible. Successful implementation of strategy is very important. This is the most crucial step in the whole process since it involves many factors besides the ability of manger. This includes the adoption of change by the employees, their commitment levels, and the enthusiasm towards their jobs. Most often the business organisations fail to achieve their desired targets since they fail to implement their s trategies in a successful manner or fail to get support from their employees. The final stage is the strategy evaluation. After the implementation it is important for the managers to test the effectiveness of the strategy. The strategy of a company requires constant updating. With the changing conditions of market and industry it is important for an organisation to keep its strategy in tact with the changing environment. An out dated strategy cannot fulfil the needs of today's global environment. In order to go through the updating process the organisations should carry on

AT&T T-MOBILE MERGER Research Paper Example | Topics and Well Written Essays - 2000 words

AT&T T-MOBILE MERGER - Research Paper Example The merger, which was announced in March 2011, aims at expanding the financial soundness of the companies by increasing total sales. This paper evaluates the issues that surround the merger of the two companies. In order to evaluate the implications of the merger between the two companies, the paper will analyze the perspectives of the AT&T Company as well as the views of the government and the competitors. Telecommunication Market The US telecommunication industry is growing at a faster rate due to the high demand of the speedy services and broadband. The industry has been oligopolized by the consolidation of the telecommunication companies especially in 1990s. In order to acquire market power, telecommunication companies in US have emulated merger and acquisition resulting to a competitive edge in the local and international markets. Major mergers include Bell Atlantic and GTE in 2000, Cingular and AT&T Wireless in 2004 as well Nextel and Sprint merger of 2005. One of the major asp ects that have resulted to the success of the telecommunication industry is that it is capital intensive. For example, in 2006-2009, more that $100 billion was invested in the industry by various companies. As a result, there has been a tremendous increase in the number of cell sites. Major players in the US telecommunication market include. ... Costs and benefits of the merger from AT&T perspective One of the benefits of the merger based on AT&T perspective is that it will create 5,000 new call centers in the US market. In this way, the company depicts that the level of household income will increase as a result of creation of more employment opportunities. In order to indicate that the merger will increase services and reduce prices within the US telecommunication market, the company provided an economic model to the Federal Communications Commission (James 2). AT&T Company aims at displacing Verizon Company in the market. According to the company top level management team, the merger will reduce the congestion experienced in its network. In addition, AT&T argues that the merger will result to the economies of scale. This will be achieved since the company is a large entity and its average cost will be reduced. Other aspects of economies of scale that will emerge include technical and financial economies (Carol 46). In thi s regard, the profitability of the company will be greatly enhanced since the costs of production will be allocated among many units. In order to ensure growth of the telecommunication market in US, the company management depicts that a significant portion of revenue that will be generated which is estimated to be more than $70 billion, will be allocated to innovation. The improvement of the telecommunication technologies will not only lead to effective communication within the US but also it will generate employment opportunities and foster US economic growth (Berkowitz 25). Additionally, the merger will enable the company to face off international competitors. This will ensure that consumers enjoy quality services with low costs. As a

Acute Renal Failure Essay Example | Topics and Well Written Essays - 1250 words

Acute Renal Failure - Essay Example This paper is going to examine the Gordon’s Functional health patterns as well as Myra Levine’s Model is relation to how acute renal failure affects the patient. A specific diet and treatment for renal failure will depend on the patient’s age, the severity and other medical conditions. Nutrition’s affect on renal failure has been studied extensively and published on scientific reports. For example, Dr. T. A’s â€Å"Primer on Kidney Disease† recommends a 0.8 to 1 g protein of body weight per kilogram each day of protein in chronic kidney disease. During dialysis, this can increases from 1.2 to 1.3 g/kg each day. Gordon’s Functional Health Patterns Marjorie Gordon developed functional health patterns to form a guideline when it comes to the establishment of a nursing data base that is comprehensive. She placed the patterns into different categories making it possible for a data collection process that is standardized and systematic (Dunn and Hood, 2009). These patterns have assisted nurses over the years in determining different human and health function aspects; a) Health Perception and Health Management. This category focuses on an individual’s perceived health level as well as well-being. ... Here, the evaluation of local supplies adequacy takes place. c) Elimination. This area mainly concerns itself with excretory patterns experienced on the skin, bladder and bowel. Excretory issues like constipation, diarrhea, incontinence and urinary retention can be easily identified d) Activity and Exercise. Focused is directed to the daily living activities that need energy expenditure, and they include leisure activities and exercise. e) Sleep and Rest. The individual’s rest, sleep and relaxation practices are assessed. Sleep patterns that are dysfunctional, sleep deprivation responses and fatigue can be identified. f) Self-Perception and Self-Concept. The individual’s attitude towards themselves is the issue of concern and this includes body image, identity, and self-worth. The identification process in this case concerns itself with the self-esteem level and threats response to the individual self concept (Dunn, 2009). g) Roles and Relationships. The role played by an individual is the one being assessed as well as how the individual relates with others. h) Sexuality and Reproduction. Person satisfaction or in some cases dissatisfaction in relation to reproductive functions and sexuality patterns are to be assessed under this category. i) Coping and Stress Tolerance. The individual’s stress perception and the way he or she copes with stress are examined. j) Values and Belief. The belief and values of an individual are assessed and this includes the individual’s spiritual beliefs. Myra Levine’s Model In her model, Myra came up with four principles that were meant to serve nurses as a guide to promoting wholeness: 1. Conservation energy. The interventions by nurses have to be gauged on the individual capacity so as to give room for

Blue Brain Essay Example for Free

Blue Brain Essay Today scientists are in research to create an arti? cial brain that can think,respond, take decision, and keep anything in memory. The main aim is to uploadhuman brain into machine. So that man can think, take decision without any effort. After the death of the body, the virtual brain will act as the man. So, even after thedeath of a person we will not loose the knowledge, intelligence, personalities, feelingsand memories of that man, that can be used for the development of the human society. Technology is growing faster than every thing. IBM is now in research to create avirtual brain, called â€Å"Blue brain†. If possible, this would be the ? rst virtual brainof the world. IBM, in partnership with scientists at Switzerland’s Ecole Polytech-nique Federale de Lausanne’s (EPFL) Brain and Mind Institute will begin simulatingthe brain’s biological systems and output the data as a working 3-dimensional modelthat will recreate the high-speed electro-chemical interactions that take place withinthe brain’s interior. These include cognitive functions such as language, learning,perception and memory in addition to brain malfunction such as psychiatric disorderslike depression and autism. From there, the modeling will expand to other regions of the brain and, if successful, shed light on the relationships between genetic, molecularand cognitive functions of the brain. The human brain has 100 billion neurons, nerve cells that enable us to adapt quickly to an immense array of stimuli. We use them to understand and respond to bright sunlight, a honking horn, the smell of chicken frying and anything else our sensors detect. To better understand some of those responses, researchers in Lausanne, Switzerland, recently launched an ambitious project called Blue Brain, which uses IBMs eServer Blue Gene, a supercomputer capable of processing 22. 8 trillion floating point operations per second (TFLOPS). Blue Brain is modeling the behavior of 10,000 highly complex neurons in rats neocortical columns (NCC), which are very similar to the NCCs in a human brain. The NCCs run throughout the brains gray matter and perform advanced computing. They are 0. 5mm in diameter and 2mm to 5mm in height and are arranged like the cells of a honeycomb. The first objective of Blue Brain is to build an accurate software replica, or template, of an NCC within two to three years, says Henry Markram, the principal researcher on Blue Brain and a professor at Ecole Polytechnique Federale de Lausanne (EPFL). That first template will be modified for NCCs found in different brain regions and species, and then all the NCCs will be replicated to build a model of the neocortices of different species, he says. Such models will shed light on how memories are stored and retrieved, Markram says. This could reveal many exciting aspects of the [brain] circuits, such as the form of memories, memory capacity and how memories are lost. The modeling can help find vulnerabilities in the neocortex, which is useful because thats where brain disorders often originate. We may also be able to work out the best way to compensate and repair circuit errors, Markram says. The model could be used to develop and test treatment strategies for neurological and psychiatric diseases, such as autism, schizophrenia and depression, he adds. Having an accurate computer-based model of the brain would mean that some major brain experiments could be done in silicon rather than in a wet lab. A simulation that might take seconds on the supercomputer could replace a full days worth of lab research, Markram estimates. Ultimately, simulated results of brain activity could be matched with recorded brain activity in a person with a disease in order to reverse-engineer the circuit changes in diseases, he says. The real value of a simulation is that researchers can have access to data for every single neuron, adds IBMs Charles Peck, head of the Blue Brain project for IBM Research.

Benefits of Foreign Direct Investment

Benefits of Foreign Direct Investment Do Host Countries Benefit From Foreign Direct Investment? Evidence From Developing Economies Executive Summary The multinational companies (MNCs) and associated foreign direct investment (FDI) play an important role in international economy. It is well-known that FDI activity can bring many significant effects to host countries. In this essay I estimate such effects from three different aspects: The first part I focus on the relation between FDI and host country wages. Previous studies show that it is a universal phenomenon that the wages in foreign companies are higher than domestic companies. The FDI activity has a positive effect to the overall wage levels of the host countries, although wages spillovers to domestic companies are not always exist. The second part I focus on the relation between FDI and host country productivity. Foreign companies have higher productivity than domestic companies; it can be supported by most of the available studies no matter what measures have been used. Although some findings reflected that local firms in developing countries can benefit from FDI by productivity spillovers, in more cases, the productivity spillovers are not significant, even negative. The third part I focus on the relation between FDI and host countrys economic Growth. The result shows that developing countries can benefit from FDI and achieve economic growth. Overall, the host countries, especially the developing countries, can benefit from foreign direct investment. 1. Introduction The worldwide spread of multinational companies (MNCs) and associated foreign direct investment (FDI) play an important role in reconstructing economy pattern of the world. It is well-known that FDI activity can bring many significant effects to host countries development. In this essay I will estimate such effects from three different aspects- the effect in wages, the effect in productivity and the effect in economic growth- by reviewing numerous relative studies and try to find out whether host countries, especially the developing countries, can get benefits from foreign direct investment. 2. FDI And Host Country Wages In this section, I will explain to what extend does FDI influence host countries wages level. Whether local firms could benefit from the entrance or existence of foreign companies will be analyzed based on the previous studies. Firstly, let us take a look at the difference between foreign companies and domestic companies in regard to wages level. Almost all the available studies proved that foreign companies did pay higher wages in developing countries. Haddad and Harrison (1993) made a research on different companies performance in Morocco. They found that in unweighted means, foreign firms paid about 70% higher wages than domestic firms. According to weighted means, the foreign companies still paid higher real wages than domestic companies (PP.58-59). Higher wages paying by MNCs was also supported by some studies of other developing countries, such as Indonesia (Hill, 1990, Manning 1998, Lipsey and Sjà ¶holm, 2001). Lipsey and Sjà ¶holm (2001) reported that when taken the educational level into account, blue-collar workers can get 25% higher wages and white-collar workers can get 50% higher wages in foreign companies. In the conclusion part of this paper, the author stated â€Å"those higher wages for workers of a given educational level do not reflect only the greater size and larger inputs per worker in foreign plants, or their industry or location† (p.13). If considered all these factors, the foreign companies paid 12% and 20% more wages than domestic companies for blue-collar workers and white-collar workers respectively. Another evidence is taken by Ramstetter (1999), he did an research in five East Asian economies (Hong Kong, Indonesia, Malaysia, Singapore and Taiwan) and made a report that wages in foreign plants were higher than domestic firms over 14-23 years, but the differences were not so significant in Singapore and Taiwan. It is a universal phenomenon that the wages in foreign companies are higher than domestic companies. Lipsey (2002) gave several explanations of this phenomenon. Firstly, higher wages may be caused by host-country regulations. Foreign firms are required to pay a higher price to the same quality workers in order to keep a good relationship with the host countries. Secondly, it could regard as compensation for the workers because they tend to choose local companies rather than foreign companies. Thirdly, as the foreign companies possess some advanced technology, they would rather pay more money to the employees to reduce the technology leaking resulted by stuff turnover. Last, the higher wages could count as an expense for attracting better employees because the foreign companies are not familiar with the labor market in host countries. Whether higher wages paid by foreign firms would affect the wages level in domestic firms and then change the wages level in host countries is another important question. The effects in wages of the local firms in host countries are referred as wage spillovers. Many studies focused on such wage spillovers as well as the effect to the overall wage level of the host countries taken by FDI. Aitken, Harrison, and Lipsey (1996) investigated the relationship between wages level and FDI in Venezuela and Mexico and found â€Å"no evidence of wage spillovers leading to higher wages for domestic firm†(Aitken et al., 1996, p.369). The lack of wages spillovers is in line with the different wages level between foreign and domestic companies. But there was a positive relationship between foreign ownership shares and averages industry wages, which means higher foreign ownership tend to increase industry wages. Besides, the effect was more significant for well skilled workers. The wage differ ences can be explained by â€Å"the greater human capital formation in foreign firms and lower turnover† (Aitken et al., 1996, p.369), well the increasing industry wages can be explained by the raising demand of labor in the foreign companies. Lipsey and Sjà ¶holm (2001) calculated the wage spillovers caused by FDI in Indonesia and found out foreign ownership could affect the wage level in domestic companies even if the difference in wage levels is not significant. Higher foreign ownership tend to increase the wage level of domestic companies, especially for white-collar than for blue-collar workers. We can conclude that the FDI activity has a positive effect to the overall wage levels of the host countries as the higher wages in foreign companies can increase the average wage level of the host countries, although wages spillovers to domestic companies are not always exist. As Lipsey (2002) summarized, the positive effect might caused by the higher wages paid by the foreign firms if there are no wages spillover to domestic companies; if there are positive wage spillovers, both higher wage level in foreign companies and the positive spillovers to domestic companies can contribute to the overall wage increasing; even when foreign companies take a negative effect to the wages of domestic companies, the negative spillovers could be offset by foreign companies higher wages, so it could not impact the wage level increasing in the host countries. 3. FDI And Host Country Productivity In this section, I will review the previous literatures based on two questions. The first one is whether the productivity is higher in foreign companies than domestic companies in developing countries. Only if the existence of higher productivity has been proved in foreign companies could the productivity spillover of FDI take place in developing countries. The second one is whether the higher productivity in foreign companies spills over to domestic companies. According to previous studies, comparisons of productivity between foreign-owned plants and domestic-owned plants were focused on the manufacturing sectors in developing countries. Lipsey (2002) gave a summary of Blomstrà ¶m and Wolffs working paper. They found that by measuring both value-added and gross output from manufacturing data of Mexcican in 1970, the productivity of foreign companies was more than twice of domestic companies on average. When comparing with domestic companies, the labor productivity in foreign companies was much higher in 20 manufacturing industries. They also found that the capital intensity in foreign companies was 2.5 times higher than Mexican domestic companies. Sjà ¶holm (1999, p.55) in his article examined intra-industry spillovers from FDI in the manufacturing sector of Indonesian. He used micro-level data to examine the difference in labour productivity between foreign and domestic companies in 28 industries. It was proved that technology level was higher in foreign firms than domestic firms in 26 out of 28 industries. A similar conclusion can be found in a working paper written by Okamoto and Sjà ¶holm (1999) which published in the same year. They reported in Indonesia, higher foreign shares of gross output than foreign share of employment between 1990 and 1995 indicated that foreign-owned companies had higher labor productivity. Many other studies also showed that in developing countries, the foreign companies have higher productivity than domestic companies. For Morocco, Haddad and Harrison (1993) compared the â€Å"deviation of firm productivity from each sectors best-practice frontier† in 18 industries from 1985 to 1989. They found a higher output per worker and a smaller deviation from best-practice frontiers in foreign companies than in domestic companies among total 12 industries. For Uruguay, value added per worker was used to estimate the difference in productivity between foreign and domestic owned companies. Result revealed that in 1988, the productivity in foreign firms was about 2 times as in domestic firms on average (Kokko, Zejan, and Tansini, 2001). According to a research of Taiwan manufacturing sector in 1991, Chuang and Lin (1999) found that labor productivity of MNCs was much higher than local firms, but total factor productivity of foreign companies was only slightly higher than lo cal companies. The study for Turkey between 1993 -1995 in which different elements of the production function were taken into account by Eridilek (2002), as well as the study for five Ease Asian economies (Hong Kong, Indonesia, Malaysia, Singapore and Taiwan) in which Ramsteteer (1999) used value added per employee to measure labor productivity, both found that the average productivity of were significant higher in MNCs than in domestic firms. From all evidence mentioned above, the conclusion that â€Å"foreign companies have higher productivity than domestic companies† can be supported in developing countries no matter what measures have been used. This phenomenon may be resulted from â€Å"larger scale of production† or â€Å"higher capital intensity† in the foreign companies (Lipsey, 2002, p. 40). Before move to the research on whether host countries could get benefit from FDI in respect of productivity growth, we should first make clear when the productivity spillovers take place. Blomstrà ¶m and Kokko (1998) expressed that the productivity spillovers occur when establishment of foreign companies result in promoting the productivity and efficiency of the local companies in host countries, and the foreign companies can not completely internalize the value of these benefits. Another reason that productivity spillovers take place is the domestic companies are forced to improve the efficiency of using their existing technology and resources because the entry of foreign companies carried fierce competition to the host countries. The severe competition also leads the domestic companies to pursue new technologies which can result in the productivity spills out. Besides, we should also classify the different types of spillovers. Horizontal spillovers are the effects from foreign to local firms belonging to the same industry. Vertical spillovers occur both in upstream industries and downstream industries (Javrcik, 2004). For horizontal spillovers studies, Aitken and Harrison (1999) used a panel data of Venezuelan companies during 1976 to 1989, concluded that there are â€Å"no evidence supports the existence of technology spillovers† between foreign and local companies (p.617). Konings (2001) also used panel data to study the effect of FDI in Bulgara, Romania and Poland. According to their conclusion, they did not find any evidence of spillovers in these emerging market economies. Such results have also been supported by Djankov and Hoekman (2000). However, this conclusion can not be generalized from all the developing countries. Damijan et al. (2003) used firm-level data to study 8 transition countries between 1994 and 1998, found spi llovers from foreign to local companies were positive in Romania ( p.11). Besides, Kinoshita (2001) proved that the RD-intensive sectors of Czech Republic have positive horizontal spillovers. Compared with horizontal spillovers, â€Å"It is quite upbeat about the existence of vertical spillover† (Javrcik and Spatareanu, 2005, P.54). Since many existing articles have provided evidence of vertical spillovers in developing countries. In another paper of Javrcik (2004), firm-level panel data was used in testing the productivity spillovers in Lithuania. The results revealed positive spillovers from FDI in upstream sectors but the positive productivity spillovers were associated with partially owned foreign investments. Such existence of vertical spillovers has also been provided by Blalock and Gertler (2004) and Schoores and van der Tol (2001). Although most of the articles have a common idea on the existence of vertical spillovers, they cannot reach agreements in some questions, such as whether there are some positive spillovers carried by FDI in upstream industries. Javrcik and Spatareanu (2005) gave a theoretical assumption that if multinationals can benefit from the better performance of intermediate input suppliers, they would not take measures to prevent productivity spillovers from happening. Thus, a spillovers-channel would be established between foreign companies and their suppliers belonging to local firms. In their opinion, positive effects of FDI might take place in upstream industries as the foreign companies would impose an increasing demand and better quality of intermediate products, such requirements would stimulate local suppliers to improve their technology in productive activity, meanwhile, they can benefits from scale economies. It seems reasonable but is not always the case in reality. Lipsey (2002) in his article cited an unpublished paper written by Aitken and Harrison (1991), which showed â€Å"negative effects of foreign direct investment in an industry on productivity in upstream industries† in Venezuela (p.41). They also provided a possible reason that â€Å"foreign firms shift the demand for intermediate inputs from domestic to foreign producers, reducing the scale of output, and there fore productivity, in domestic production† (p.41). Other factors that could influent spillovers are also existent. Xu (2000) used data from 1966 to 1994 of US manufacturing MNCs in 40 countries to investigate whether MNCs can help international technology diffusion. The paper found a weak evidence of technology diffusion from US MNCs in less developed countries (LDCs). The explanation given by the author is most LDCs cannot reach â€Å"a human capital threshold of about 1.9 years (in terms of male secondary school attainment) to benefit from technology transfer of US MNE affiliates† (p. 491). A conclusion that â€Å"the technology spillover effects brought by FDI are not significant in less developed countries† could be abstracted from this paper. Some studies did support that local firms in developing countries can benefit from FDI, because productivity spillovers from foreign firms can help local firms to improve their existing technology as well as achieve scale economies. However, in more cases, the spillovers are not significant, even negative. So we can not make a simple conclusion as whether the positive spillovers are really existent is depend on different factors in different circumstances. 4. FDI And Host Countrys Economic Growth Economic growth, which is a common objective for all developing countries, can be achieved from productivity spillovers. Several authors have studied the interaction between FDI and economic growth in developing countries. De Mello (1999) found that spillovers of technology and knowledge from the foreign countries were two determinants of long-term growth in host countries and FDI has positive effects on economic growth in developing countries. Bende-Nabende (2001) used annual data from 1970 to 1996 studied on Asian countries and showed that in Indonesia, Malaysia and Philippines there is a positive impact carried by FDI. Bengoa and Sanchez-Robles (2003) used data between 1970 and 1999 of Latin American countries and find that positive effect only take place in countries with more economic freedom. According to Kohpaiboon (2003) and Marwah and Tavakoli (2004), a positive correlation between FDI and GDP growth were showed in Thailand, Malaysia and Philippines. Moreover, several papers focused on FDI effect in China also reflected positive effect on economic growth (Vu et al., 2008, p. 546). However, not all the studies supported the positive effect of FDI in developing countries. In the research of Blomstrà ¶m, Lipsey, and Zejan (1994), developing countries were separated into two groups the higher income countries and the lower income countries -and reported that only the higher-income group FDI inflow lead to economic growth. Through the analysis on 69 developing countries in the period of 1970 to 1989, Carkovic and Levine (2002) used panel data to test the correlation between FDI and developing countries economic growth. The results showed that the effect of FDI inflows was not significant. The different methods and data choosing may lead to such different results. Some unknown factors would also affect the results. But they do not have so much impact to our conclusion. Based on the findings of previous studies, generally speaking, developing countries can benefit from FDI and achieve economic growth, 5. Conclusion The propose of this essay is try to estimate whether developing countries can get benefits from foreign direct investment. The effect of FDI has been classified into three aspects. Firstly, it is a universal phenomenon that the wages in foreign companies are higher than domestic companies. The FDI activity has a positive effect to the overall wage levels of the host countries, although wages spillovers to domestic companies are not always exist. Secondly, â€Å"foreign companies have higher productivity than domestic companies† can be supported by most of the available studies no matter what measures have been used. Although some findings reflected that local firms in developing countries can benefit from FDI by productivity spillovers, in more cases, the productivity spillovers are not significant, even negative. Thirdly, developing countries can benefit from FDI and achieve economic growth. Overall, we can get a positive conclusion that the host countries, especially the dev eloping countries, can benefit from foreign direct investment. References Aitken, B., Harrion, A., Lipsey, R. E., (1996) ‘Wages and foreign ownership: A comparative study of Mexico, Venezuela, and the United States, Journal of International Economics, Vol. 40 Issue 3-4, pp.345-371 ScienceDirect [Online]. Available at: http://www.sciencedirect.com/ (Accessed: 20 December 2009) Bende-Nabende, A., (2001) ‘ FDI, regional economic integration and endogenous growth, some evidence from Southeast Asia, Pacific Economic Revies, Vol. 6 Issue 3, pp.383-399 InterScience [Online]. Available at: http://www3.interscience.wiley.com / (Accessed: 20 December 2009) Blalock, Garrick. ‘Technology from Foreign Direct Investment: Strategic Transfer through Supply Chains. Paper presented at the Empirical Investigations in International Trade Conference at Purdue University, November 9-11, 2001 (part of doctoral research at Haas School of Business, University of California Berkeley). Blomstrà ¶m, M. and Kokko, A., (1998) ‘Multinational Corporations and Spillovers, Journal of Economic Surveys, Vol. 12 Issue 3, pp.246-277 EBSCO [Online]. Available at: http://web.ebscohost.com/ (Accessed: 20 December 2009) Borensztein, E., Goregorio, D. J., Lee, J-W (1998) ‘How does foreign direct investment affect economic growth?, Journal of International Economics, Vol. 45 Issue 1, pp.115-135 ScienceDirect [Online]. Available at: http://www.sciencedirect.com/ (Accessed: 20 December 2009) Carkovic, M. V. and Levine, R. (2002) ‘Does Foreign Direct Investment Accelerate Economic Growth?, University of Minnesota Department of Finance working Paper SSRN[Online]. Available at: http://papers.ssrn.com/ (Accessed: 20 December 2009) Chakraborty, C. and Basu, P., (2002) ‘Foreign direct investment and growth in India: a cointegration approach, Routledge, part of the Taylor Francis Group, Vol. 34 Issue 9, pp.1061-1073 [Online]. Available at: http://www.ingentaconnect.com/ (Accessed: 20 December 2009) Chuang, Y. C. and Lin C. M., (1999) ‘Foreign Direct Investment, RD, and Spillover Efficiency: Evidence from Taiwans Manufacturing Firms, Journal of Development Studies, Vol. 35 Issue 4, pp.117-137 EBSCO [Online]. Available at: http://web.ebscohost.com/ (Accessed: 20 December 2009) Damijan, J. P., Knell, M. S., Majcen, B., Rojec, M (2003) ‘The role of FDI, RD accumulation and trade in transferring technology to transition countries: evidence from firm panel data for eight transition countries, Economic Systems, Vol. 27 Issue 2, pp.189-204 EconPapers [Online]. Available at: http://econpapers.repec.org/ (Accessed: 20 December 2009) De Mello, Jr.,L.R., (1999) ‘FDI-led growth: evidence from time series and panel data , Oxford Economic Papers, Vol. 51 Issue 1, pp.133-151 OXFORD FOURNALS [Online]. Available at: http://oep.oxfordjournals.org/ (Accessed: 20 December 2009) Gà ¶rg, H. and Greenaway, D., (2000) ‘Multinational enterprises, technology diffusion, and host country productivity growth , Research Paper 2000/12, Centre for Research on Globalisation and Labour Markets, University of Nottingham. Available at: http://globalisationandeconomicpolicy.com (Accessed: 20 December 2009) Haddad, M. and Harrison, A., (1993) ‘Are there positive spillovers from direct foreign investment? Evidence from panel data for Morocco , Journal of Development Economics, Vol. 42 Issue 1, pp.51-74 RePEc [Online]. Available at: http://repec.org/ (Accessed: 20 December 2009) Javorcik, B. S. and Spatareanu, M., (2005) ‘Does foreign direct investment promote development?, PP. 45-71, Available at: www.economics.ox.ac.uk (Accessed: 20 December 2009) Javorcik, B. S. (2004) ‘Does Foreign Direct Investment Increase the Productivity of Domestic Firms? In Search of Spillovers through Backward Linkages , The American Economic Review, Vol. 94 Issue 3, pp.605-627 JSTOR [Online]. Available at: http://www.jstor.org/ (Accessed: 20 December 2009) Kathuria, V., (2001) ‘Productivity Spillovers from Technology Transfer to Indian Manufacturing Firms, Journal of International Development, Vol. 12 Issue 3, pp.343-369 InterScience [Online]. Available at: http://www3.interscience.wiley.com/cgi-bin/home (Accessed: 20 December 2009) Kohpaiboon,A., (2003) ‘Foreign trade regimes and the FDI-growth nexus: a case study of Thailand , Journal of Development Studies, Vol. 40 Issue 2, pp.55-69 RePEc [Online]. Available at: http://repec.org/ (Accessed: 20 December 2009) Kokko, A., Zejan, M., Tansini, R., (2001) ‘Trade Regimes and Spillover Effects of FDI: Evidence from Uruguay, Economics of Transition, Vol. 137 Issue 1, pp.124-149 RePEc [Online]. Available at: http://repec.org/ (Accessed: 20 December 2009) Konings, J., (2001) ‘The effects of foreign direct investment on domestic firms: Evidence from firm-level panel data in emerging economies, Economics of Transition, Vol. 9 Issue 3, pp.619-633 EBSCO [Online]. Available at: http://web.ebscohost.com/ (Accessed: 20 December 2009) Lipsey, R. E. and Sjà ¶holm (2001) ‘Foreign Direct Investment and Wages in Indonesian Manufacturing, NBER Working Paper No. 8299, Cambridge, MA, National Bureau of Economic Research. Available at: www.nber.org/ (Accessed: 20 December 2009) Lipsey, R. E., (2002) ‘HOME AND HOST COUNTRY EFFECTS OF FDI , NBER Working Paper No. 9293*Issued in October 2002 NBER Program(s): NBER [Online]. Available at: http://www.nber.org (Accessed: 20 December 2009) Marwah, K. and Tavakoli, A. (2004) ‘The effect of foreign capital and imports on economic growth: further evidence from four Asian countries (1970-1998) , Journal of Asian Economics, Vol. 15 Issue 2, pp.399-413 ScienceDirect [Online]. Available at: http://www.sciencedirect.com/ (Accessed: 20 December 2009) Okamoto, Y. and Sjà ¶holm, F., (1999) ‘FDI and the Dynamics of Productivity: Microeconomic Evidence, Working Paper Series in Economics and Finance, No. 348, Stockholm School of Economics, December. RePEc [Online]. Available at: http://repec.org/ (Accessed: 20 December 2009) Ramstetter, E. D., (1999) ‘Comparisons of Foreign Multinationals and Local Firms in Asian Manufacturing Over Time, Asian Economic Journal, Vol. 13 Issue 2, pp.163-203 EBSCO [Online]. Available at: http://web.ebscohost.com/ (Accessed: 20 December 2009) Sanchez-Robles, B. and Bengoa-Calvo, M. (2002) ‘ FDI, economic freedom, and growth: new evidence from Latin America, Universidad de Cantabria, Economics Working Paper No. 4/03. Available at SSRN: http://ssrn.com/abstract=353940 or doi:10.2139/ssrn.353940 (Accessed: 20 December 2009) Sjà ¶holm, F., (1999) ‘Technology Gap, Competition and Spillovers from Direct Foreign Investment: Evidence from Establishment Data, The Journal of Development Studies, Vol. 36 Issue 1, pp.53-73 RePEc [Online]. Available at: http://repec.org/ (Accessed: 20 December 2009) Vu, T. B., Gangnes, B., Noy, I. (2008) ‘Is foreign direct investment good for growth? Evidence from sectoral analysis of China and Vietnam , Journal of the Asia Pacific Economy, Vol. 13 Issue 4, pp.542-562 informaworld [Online]. Available at: http://www.informaworld.com/ (Accessed: 20 December 2009) Xu, B, (2000) ‘Multinational enterprises, technology diffusion, and host country productivity growth , Journal of Development Economics, Vol. 62 Issue 2, pp.477-493 RePEc [Online]. Available at: http://repec.org/ (Accessed: 20 December 2009)